Thermal, phase transition and spectral studies in erythromycin pseudopolymorphs: dihydrate and acetone solvate by Zhanzhong Wang, Jingkang Wang, and Leping Dang

Crystal Research and Technology

Cryst. Res. Technol. 41, 1219 (2006) - Abstract -

Thermal, phase transition and spectral studies in erythromycin pseudopolymorphs: dihydrate and acetone solvate

Zhanzhong Wang, Jingkang Wang, and Leping Dang

School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, P. R. China

Keywords	erythromycin pseudopolymorphs, characterization, thermal behavior, thermal kinetic analysis
PACS	65.40.-b, 68.18.Jk, 61.50.-f, 68.60.Dv
DOI	10.1002/crat.200610753

The thermal, phase transition and spectral studies of erythromycin A dihydrate and acetone solvate were performed by Differential Scanning calorimetry (DSC), Thermo Gravimetry (TG-DTA), X-Ray Powder Diffraction (XRPD) and Fourier Transform Infra-Red (FTIR) spectrum. The non-thermal kinetic analysis of erythromycin A dihydrate was carried out by DSC at different heating rates in dynamic nitrogen atmosphere. The result showed that heating rate has substantial influence on the thermal behavior of erythromycin dihydrate. The Arrhenius parameters were estimated according to the Kissinger method.

The full text of this paper in pdf-Format:

If you have come directly to this page, click this symbol

to go to the CRT homepage.