Crystal Research and Technology
Cryst. Res. Technol. 42, 517 (2007) - Abstract -

Structure of (dimethyl sulfoxide-S){glyoxylic acid thiosemicarbazonato(2-)-O,N,S}platinum(II)

N. I. Dodoff, D. Kovala-Demertzi*, J. Kuduk-Jaworska**, M. Kubiak**, and A. Kochel**

Institute of Molecular Biology, Bulgarian Academy of Scuiences, Acad. G. Bonchev Street, Block 21, 1113 Sofia, Bulgaria
*Department of Chemistry, University of Ioannina, 451 10 Ioannina, Greece
**Faculty of Chemistry, University of Wroc³aw, 14 F. Joliot Curie Street, 50-383 Wroc³aw, Poland

Keywords platinum(II), thiosemicarbazone, glyoxylic acid, dimethyl sulfoxide, crystal structure
PACS 61.66.Fn
DOI 10.1002/crat.200610858

A crystal of the title complex [Pt(DMSO)(GT)] (1a), where H2GT = glyoxylic acid thiosemicarbazone, has been characterized by X-ray crystallography and its structure has been compared with that of the recently described cytotoxic complex [Pt(DMSO)(GT)].DMSO (1). The crystal of 1a is monoclinic; space group P21/n; unit cell dimensions: a = 7.3270(10), b = 10.313(2), c = 13.706(3) Å, β = 101.93(3)°; V = 1013.3(3) Å3; Z = 4. The Pt(II) ion is approximately planar tetragonal coordinated by the carboxylato oxygen, azomethine nitrogen and thiolato sulfur atom of the doubly deprotonated H2GT molecule, and the sulfur atom of DMSO. The two five membered chelate rings are almost coplanar. In distinct with 1, the sulfoxide oxygen atom and thiolato sulfur atom are in gauche position. A system of hydrogen bonds of the type N-H...O involving the amino, carboxylato and sulfoxide groups links the complex molecules within the unit cells. The π-π stacking pattern between the chelate rings in 1a involves centrosymmetric pairs of complex molecules and differs from that in 1.




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